Baby · Immunisation
Baby Vaccine Schedule (UK NHS & US CDC)
Full routine vaccine schedule for babies and toddlers — toggle between UK NHS Green Book and US CDC ACIP. Plus catch-up if behind, side effects, prematurity, the MMR-autism myth debunked.
Last reviewed 28 May 2026
Personalised immunisation schedule
When are my baby's vaccinations?
Use the calculator above to see vaccines by age. Toggle between UK NHS and US CDC schedules. Both are evidence-based; differences reflect national decisions (epidemiology and cost-effectiveness thresholds), not vaccine quality.
UK NHS routine schedule (quick reference)
- 8 weeks: 6-in-1 (diphtheria, tetanus, pertussis, polio, Hib, hepatitis B), rotavirus (oral), MenB.
- 12 weeks: 6-in-1, pneumococcal (PCV), rotavirus.
- 16 weeks: 6-in-1, MenB.
- 1 year: Hib/MenC, MMR, PCV, MenB.
- 2-15 years (annual): influenza nasal spray.
- 3 years 4 months: pre-school booster (4-in-1) + MMR (2nd dose).
- 12-13 years: HPV.
- 14 years: 3-in-1 teenage booster + MenACWY.
US CDC schedule highlights
- Birth: hepatitis B.
- 2 months: hepatitis B, rotavirus, DTaP, Hib, PCV, IPV.
- 4 months: same set.
- 6 months: hepatitis B, rotavirus, DTaP, Hib, PCV, IPV, annual influenza, annual COVID.
- 12-15 months: MMR, varicella, hepatitis A (start), PCV, Hib.
- 4-6 years: DTaP, IPV, MMR, varicella.
Why do babies need so many vaccines so early?
Newborns are most vulnerable to several serious infections — pertussis, Hib meningitis, pneumococcal disease, rotavirus, hepatitis B. Maternal antibodies fade by 6-12 weeks. The 8-, 12-, 16-week timing is when babies’ immune systems are mature enough to respond, just as maternal protection drops.
Multiple shots same day are not “overloading” — the immune system handles thousands of antigens daily from food, dust, normal bacteria. Adding 3 vaccines is a tiny fraction of normal antigen exposure.
What are the side effects?
Mild and short-lived in most babies:
- Within 24 hours: redness, swelling, soreness at injection site.
- Mild fever (especially MenB and PCV).
- Fussiness, reduced appetite, drowsiness for a feed or two.
- By 48 hours: usually back to normal.
MenB is the most reactogenic — fever very common. NICE recommends prophylactic paracetamol (the ONLY vaccine where this is advised): 2.5 ml infant paracetamol at vaccination time, then again at 4 and 8 hours. Doesn’t reduce vaccine effectiveness.
Severe reactions (anaphylaxis) are extremely rare — about 1 in a million doses. That’s why babies wait 15 minutes at the clinic.
Catch-up — if my baby is behind
Catch-up is straightforward. UK: Green Book Chapter 11 specifies intervals for delays. US: ACIP Table 2 (annual MMWR). Key principle: don’t restart any series — completed doses always count. Call your GP / HV / paediatrician to plan. Even children entering school behind can usually complete the routine schedule before age 5. See /calculators/vaccine-catchup for the catch-up calculator.
Should I delay vaccines if my baby is unwell?
A minor illness (cold, mild fever < 38 °C) is NOT a contraindication. Hold doses only for:
- Moderate-to-severe acute illness (definitely if ≥ 39 °C).
- Specific contraindications (anaphylaxis to a previous dose).
- Live vaccines in immunocompromised children.
UKHSA Green Book and CDC: babies with mild cold symptoms, mild fever, snotty nose can still be safely vaccinated.
Different scenarios — common questions answered
Scenario 1: 8-week-old, mild runny nose, due first jabs tomorrow
Proceed. Mild cold symptoms are NOT a contraindication. Skipping for minor illness is a common but unnecessary delay.
Scenario 2: 12-week-old former 30-week preterm baby
Use chronological age, NOT corrected age, for routine vaccinations. Get jabs at 12 weeks chronological. Preterm babies are MORE vulnerable to vaccine-preventable infections, not less. Apnoea monitoring for first vaccinations if very preterm (< 28 weeks corrected).
Scenario 3: 4-month-old, missed 12-week jabs at GP closure
Catch up at next available visit. The dose given at 4 months counts as the 12-week dose (just delayed). Then 16-week dose at 5 months, etc. Don’t restart.
Scenario 4: Family travelling abroad with 6-month-old
MMR can be given early (from 6 months) if travelling to a measles endemic area — this early dose doesn’t count toward routine schedule; routine MMR still given at 1 year and 3 years 4 months. Travel-specific vaccines (hepatitis A, typhoid, yellow fever in older children) per destination.
Scenario 5: Child has eczema and egg allergy — MMR safe?
YES. MMR vaccine is produced in chick embryo fibroblast cell cultures — trace egg protein only. Routine vaccination is safe even in severe egg-allergic children (UK NHS / AAP). Live attenuated flu nasal spray also safe in most egg allergy. Only yellow fever vaccine has a real egg-allergy contraindication.
The MMR-autism myth — settled science
The 1998 Wakefield paper that suggested an MMR-autism link was retracted by The Lancet in 2010 for serious methodological flaws and research misconduct; Wakefield was struck off the UK medical register. Since then, studies of over 1 million children combined:
- Madsen 2002 (Denmark, 500,000+ children) — no link.
- Jain 2015 (US, 95,000 children including high-risk autism siblings) — no link.
- Hviid 2019 (Danish cohort, 657,000 children) — no link.
Autism rates are similar in vaccinated and unvaccinated children. The increased autism prevalence reflects broader diagnostic criteria and better recognition — NOT vaccines. Withholding MMR exposes the child (and their immunocompromised contacts) to measles, mumps, rubella — all with real risks (encephalitis, orchitis, congenital rubella syndrome).
What about vaccine ingredients? (Aluminium, formaldehyde, thimerosal)
- Thimerosal — removed from all routine UK and US childhood vaccines (UK never used in childhood; US since 2001). Ethyl mercury (different from neurotoxic methyl mercury in fish) was metabolised and excreted in days anyway.
- Aluminium adjuvants — decades of safety data. Total dose across entire infant schedule is LESS than aluminium an exclusively breastfed baby takes in over the same period (FDA Mitkus 2011 model).
- Formaldehyde — trace residual from manufacturing. Your body produces 1.5 oz of formaldehyde/day naturally. Vaccine residual is 0.0001 g per dose.
- Egg protein — trace in MMR (chick embryo culture), flu vaccines. Safe in most egg allergy.
Vaccines in pregnancy
- Pertussis (whooping cough): 16-32 weeks of every pregnancy. Cuts under-3-month pertussis by ~90% via maternal antibody transfer.
- Influenza: any trimester. Protects mum from severe flu, baby through maternal antibodies for ~6 months.
- COVID: current recommendations vary by country.
- RSV: 28-32 weeks (UK NHS from autumn 2024 in some areas).
- Avoid in pregnancy: live vaccines (MMR, varicella, yellow fever, BCG).
Care guidance — the day of vaccination
- Feed before — well-fed baby is calmer.
- Bring a comfort item — muslin, soft toy.
- Stay 15 minutes after (anaphylaxis observation).
- Cuddle and feed immediately after — reduces crying.
- Paracetamol if uncomfortable: 2.5 ml infant paracetamol (60 mg). For MenB: prophylactic dosing per NICE.
- Loose-fitting clothing over injection sites.
- Cool compress if local swelling/redness.
- Watch for high fever (≥ 39 °C) lasting > 24 hours — GP review.
- Don’t worry about fussiness for 1-2 days — normal.
- Record dates in red book / immunisation record.
Sources
- UKHSA. The Green Book: Immunisation against Infectious Disease.
- CDC. Recommended Child and Adolescent Immunization Schedule, United States, 2026.
- NICE NG175. COVID-19 rapid guideline.
- Hviid A, et al. Measles, Mumps, Rubella Vaccination and Autism: A Nationwide Cohort Study. Ann Intern Med 2019;170:513-520.
- Mitkus RJ, et al. Updated aluminum pharmacokinetics following infant exposures. Vaccine 2011.
- WHO. Vaccines and immunization.