Paediatric · Dosing
Pediatric Dose Calculator
Weight-based dosing for paracetamol, ibuprofen, and common paediatric antibiotics. UK BNFC / US AAP doses. Plus safety limits, overdose thresholds, common dosing errors, when to call.
Last reviewed 31 May 2026
Weight-based medication dose (mg/kg)
Medication
Standard antipyretic / analgesic. Age ≥ 2 months and weight ≥ 4 kg (UK BNFc); from birth in some specialist contexts.
Units
Safety rules
- NEVER aspirin in under-16s with fever (Reye syndrome).
- NEVER ibuprofen under 3 months. Avoid in dehydration.
- NEVER codeine / dihydrocodeine / tramadol under 12.
- Use a dosing syringe — kitchen teaspoons are inaccurate.
- If unsure — call your GP, pharmacist, or NHS 111 / Poison Control.
Paracetamol dose
15 mg/kg every 4-6 hours, max 4 doses in 24h. MAX single dose 1 g. MAX daily 60 mg/kg/day or 4 g/day, whichever is lower.
- Newborn (under 2 months): 10 mg/kg under specialist guidance.
- 3 months - 5 years: infant paracetamol suspension 120 mg/5 ml.
- 6+ years: 250 mg/5 ml suspension or 500 mg tablets.
Ibuprofen dose
10 mg/kg every 6-8 hours, max 3 doses in 24h. MAX daily 30 mg/kg/day or 1.2 g/day, whichever is lower.
- 3+ months AND 5+ kg only — KEY restriction.
- AVOID in: dehydration, chickenpox / shingles, severe asthma, kidney impairment, peptic ulcer, bleeding disorders.
- CAN take with paracetamol — alternate every 3 hours if needed.
Weight-based dose tables
Paracetamol
- 5 kg: 75 mg = 3 ml of 120 mg/5ml suspension
- 10 kg: 150 mg = 6 ml
- 15 kg: 225 mg = 9 ml
- 20 kg: 300 mg = 12 ml
- 25 kg: 375 mg = 15 ml
- 30 kg: 450 mg = 18 ml
- 40 kg+: 500 mg single dose (adult)
Ibuprofen
- 5 kg (3+ months only): 50 mg = 2.5 ml of 100 mg/5ml
- 10 kg: 100 mg = 5 ml
- 15 kg: 150 mg = 7.5 ml
- 20 kg: 200 mg = 10 ml
- 25 kg: 250 mg = 12.5 ml
- 30 kg: 300 mg = 15 ml
- 40 kg+: 400 mg single dose
Common antibiotics & uses
- Amoxicillin — strep throat, otitis media, pneumonia (first-line).
- Augmentin / Co-amoxiclav — sinusitis, dental, beta-lactamase strains.
- Phenoxymethylpenicillin — strep throat, dental.
- Cephalexin / cefuroxime — skin infections, UTI.
- Flucloxacillin — skin / soft tissue.
- Clarithromycin / azithromycin — penicillin allergic; atypical pneumonia.
- Trimethoprim / nitrofurantoin — UTI.
- Metronidazole — anaerobes, dental, C. diff.
All weight-based dosing per UK BNFC / US BNF for Children.
Can I give paracetamol and ibuprofen together?
YES, alternating in some situations. NICE: not routinely; only if child distressed and one not enough. ALTERNATE every 3 hours (paracetamol-ibuprofen-paracetamol-ibuprofen). DON’T alternate routinely — increases dosing error risk. Record doses given. Treat discomfort, not the thermometer reading.
Paracetamol overdose
THERAPEUTIC max: 60 mg/kg/day or 4 g/day, whichever lower. ACCIDENTAL OVERDOSE: > 75 mg/kg in 24h.
CALL POISONS for any concern:
- UK: NPIS 0344 892 0111 or NHS 111
- US: Poison Control 1-800-222-1222
SIGNS of paracetamol overdose may not appear for 24-72 hours — DON’T wait for symptoms. Treatment with N-acetylcysteine (NAC) within 8 hours is very effective.
Common dosing errors
- WRONG STRENGTH suspension — 120 mg vs 250 mg vs 500 mg paracetamol all exist. Check label every time.
- KITCHEN SPOONS — vary wildly. Use syringe.
- DOUBLE-UP with cold-and-flu products containing same ingredient.
- Using age-band that’s conservative for child’s weight.
- Mistaking ml for mg or vice versa.
- Giving adult tablets to child.
- Crushing tablets that shouldn’t be crushed.
Brand vs generic medicines
- Calpol = paracetamol
- Nurofen = ibuprofen
- Anadin — mixed (DON’T USE in children — aspirin).
Generic versions equally effective and cheaper. CHECK active ingredient and strength. NEVER aspirin in under-16s with viral infection — Reye’s syndrome risk.
Different scenarios — common dosing situations
Scenario 1: 12-month-old, 9 kg, fever 38.5 °C, uncomfortable
Paracetamol 135 mg (~5.5 ml of 120 mg/5ml) OR ibuprofen 90 mg (~4.5 ml of 100 mg/5ml). Either fine. Treat comfort. Keep hydrated.
Scenario 2: 4-year-old, 16 kg, persistent fever 5 days, irritable
240 mg paracetamol (10 ml of 120 mg/5ml) OR 160 mg ibuprofen. PERSISTENT 5+ days = GP review for source (UTI, otitis media, Kawasaki, etc.). Don’t just keep medicating.
Scenario 3: 2-week-old newborn, fever 38 °C
DON’T medicate at home. NICE NG143: ANY fever under 3 months = same-day emergency assessment. Sepsis workup possible.
Scenario 4: Child with chickenpox, painful
PARACETAMOL only. AVOID IBUPROFEN in chickenpox (linked to severe skin / soft-tissue infections including necrotising fasciitis).
Scenario 5: Antibiotic prescribed for strep throat, parent unsure of dose
Check BNFC: amoxicillin 25-50 mg/kg/day in 3 doses for strep throat (max 1 g per dose). Pharmacist or GP can verify. Complete the FULL COURSE even if better.
Care guidance — medicating safely
- Weigh your child — weight-based dosing accurate.
- Use syringe not kitchen spoon.
- Check strength every time — brands have multiple strengths.
- Record doses — paper or app.
- Don’t double-dose with cold/flu products containing same ingredient.
- Read every label.
- Lock medications out of children’s reach.
- Don’t crush tablets not designed to crush (check with pharmacist).
- Complete full antibiotic course even when better.
- Don’t share antibiotics — resistance.
- If unsure — ask pharmacist (immediate, free, accessible).
Sources
- British National Formulary for Children (BNFC). Updated annually.
- NICE NG143. Fever in under 5s.
- AAP. Clinical Report: Acetaminophen / Ibuprofen for Children.
- NHS. Medicines for children.
- NPIS (UK National Poisons Information Service).
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